Montag, 19. Dezember 2016

R: Clinical Trial Simulator

The first version of the clinical trial simulator is online now.

It uses a dose-response model based on the Hill equation which basically is a saturation model. The assumption is that a cell is covered by a finite number of receptors. When the treatment is applied, a fraction of the receptors (depending on the dosage) is interacting with the treatment molecule and every interaction leads to a response. When every receptor is binding to the treatment, the response saturates.

It's based on the MSToolkit package and is hosted online at shiny apps under

Keine Kommentare:

Kommentar veröffentlichen